SORT-PGRN interaction inhibitor 1

CAS No. 100957-85-5

SORT-PGRN interaction inhibitor 1( —— )

Catalog No. M23215 CAS No. 100957-85-5

SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SORT-PGRN interaction inhibitor 1
  • Note
    Research use only, not for human use.
  • Brief Description
    SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
  • Description
    SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Neurotensin Receptor
  • Recptor
    sortilin-progranulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    100957-85-5
  • Formula Weight
    258.32
  • Molecular Formula
    C15H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    O=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.
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